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A Simple and Environmentally Benign Protocol for Biginelli Reactions Catalyzed by Silica-Bonded S-Sulfonic Acid（图）
Biginelli reaction silica-bonded S-sulfonic acid dihydropyrimidinone
2013/10/5
A protocol for the synthesis of 3,4-dihydropyrimidin-2(1H)-ones and -thiones was developed by means of a three-component condensation of an aldehyde, a β-dicarbonyl compound, and urea or thiourea in a...