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Background: It has been demonstrated that HER3 plays an important role in some human cancers and the HER3 expression is associated with worse survival in solid tumors.
Although efforts to encourage presentation with early signs of cancer has had some impact in down-staging disease at diagnosis, notably in breast cancer and melanoma, assertive, physician-initiated ...
Adolescents and young adults with cancer have unique medical and psychosocial needs. In addition to efforts aimed at improving survival, there is acknowledgement of the need to understand how social a...
Australia’s population is growing, and ageing, rapidly. It is estimated that within 50 years around one in four Australians will be aged over 65 years.1 Accordingly, the incidence of cancer – for...
Background: Diagnosis of breast cancer is completed through core needle biopsy (CNB) of the tumors but there is controversy on the accuracy of hormone receptor results on CNB specimens.
This study investigated quality of life (QOL) in patients with advanced non-small-cell lung cancer in an early phase of chemotherapy in a randomized phase III trial. QOL assessments for four domains (...
Background: Because of confusion to gastric cancers arising at the gastro-esophageal junction, true esophageal adenocarcinoma was thought to be unusual. Esophageal adenocarcinoma (EAC) is becoming mor...
The most frequently mutated tumor suppressor gene found in human cancer is p53. In a normal situation, p53 is activated upon the induction of DNA damage to either arrest the cell cycle or else induce ...

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