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Serum Lectin-Like Oxidized-Low Density Lipoprotein Receptor-1 and Adiponectin Levels Are Associated With Coronary Artery Disease Accompanied With Metabolic Syndrome
LOX-1 Coronary Artery Disease Adiponectin Metabolic Syndrome
2015/10/14
Background: Coronary artery disease (CAD) is a major public health problem for developed and developing countries and is the single leading cause of death worldwide.
Is Chemokine Receptor CCR9 Required for Synovitis in Rheumatoid Arthritis? Deficiency of CCR9 in a Murine Model of Antigen-Induced Arthritis
Chemokine Receptor CCR9 Rheumatoid Arthritis Inflammation Antigen-Induced Arthritis Mouse Mod-el Monocytes/Macrophages
2013/1/31
Objectives: Monocytes/macrophages accumulate in the synovial membrane in rheumatoid arthritis and play a key role in disease pathogenesis, contributing to inflammation, cartilage destruction and bone ...
Antitussive Effects of the Leukotriene Receptor Antagonist Montelukast in Patients with Cough Variant Asthma and Atopic Cough
atopic cough cough score cough variant asthma leukotriene receptor antagonist montelukast
2010/11/12
In patients with CVA, 2-week treatment with montelukast, clenbuterol, and montelukast plus clenbuterol all significantly decreased cough scores and treatment with montelukast plus clenbuterol was supe...
The effect of AT1 receptor blockade on bax and bcl-2 expression in bleomycin-induced pulmonary fibrosis
bcl-2 bax bleomycin pulmonary fibrosis losartan
2009/12/14
ABSTRACT
Background and the purpose of the study: Recent studies have indicated the role of apoptosis and angiotensin in the pathogenesis of bleomycin induced-pulmonary fibrosis. Losartan, an angiote...
目的: 分析幽门螺杆菌(H pylori)感染对胃黏膜癌变过程中胃泌素及受体CCK-BR基因转录和蛋白表达的影响，探讨H pylor在胃癌发生中的作用. 方法: 采用快速尿素酶试验、Giemsa染色及Warthin-Starry银染色检测H pylori;应用免疫组织化学和RT-PCR技术检测萎缩性胃炎51例，18例肠上皮化生18例，异型增生15例和胃癌组织37例中的胃泌素及受体CCK-BR蛋白和...
Effects of ACE Inhibition and AT1 Receptor Blockade on Cardiac Ischaemia-Reperfusion Induced Mortality and Cardiac Markers in Rats
Myocardial Ischemia-Reperfusion Arrhythima Cardiac Marker Troponin Captopril Losartan
2009/6/22
Many studies have established the therapeutic benefits of angiotensin-converting enzyme (ACE) inhibitors such as reducing reperfusion arrhythmias, and angiotensin II type 1 (AT1) blocker may have simi...
磺酰脲类受体基因多态性与2型糖尿病的相关性研究Study on the Relationship between Sulfonylurea Receptor 1 Gene Polymorphism and Type 2 Diabetes Mellitus
2型糖尿病 磺酰脲类受体1 基因多态性
2008/1/10
摘要 研
究磺酰脲类受体1（SUR1）基因外显子16-3c/t多态性在中国某南方汉族人群中是否为2型糖尿病的致病基因座。采用聚合酶链反应-限制酶酶切片段长度多态性（PCR-RFLP）方法对南方汉族46个2型糖尿病高发家系成员的SUR1基因外显子16的多态性进行分析。利用Mantel-Haenszel分层分析研究该基因座多态性与2型糖尿病的关系。在高发家系人群中，SUR1基因外显子16-3c/t多...
Expression of leukemia inhibitory factor receptor and gp130 in mouse uterus during early pregnancy
2007/7/28
期刊信息
篇名
Expression of leukemia inhibitory factor receptor and gp130 in mouse uterus during early pregnancy
语种
英文
撰写或编译
撰写
作者
Ni H,Ding N Z,Harper M J K,Yang Z M
第一作者单位
刊物名称
Molecular Reproduction and
...
Molecular-Based Haplotype Analysis of the β2-Adrenergic Receptor Gene (ADRB2) in Japanese Asthmatic and Non-Asthmatic Subjects
asthma haplotype Japanese population SNPs 2-adrenergic receptor
2010/11/18
Fifteen SNPs including a novel one in -839 were observed. Allele frequencies for all SNPs were similar between asthmatics and controls. We also identified 42 haplotypes and 54 diplotypes of ADRB2 in a...
Effect of a leukotriene receptor antagonist, pranlukast hydrate, on airway inflammation and airway hyperresponsiveness in patients with moderate to severe asthma
airway hyperresponsiveness airway inflammation asthma eosinophils leukotriene leukotriene receptor antagonist
2010/11/25
Asthma is characterized by chronic airway inflammation and the recruitment of inflammatory cells, typically eosinophils and lymphocytes, into the airway. Although several chemical mediators are releas...
Polymorphism of angiotensin II type 1 receptor gene in essential hypertension in Iranian population
Angiotensin Gene polymorphisms Hypertension
2010/2/4
Renin angiotensin system (RAS) has an important role in the regulation of hypertension. RAS includes angiotensinogen, Angiotensin Converting Enzyme (ACE), angiotensine II and angiotensin receptors (AG...
Role of protein kinase A in the inhibition of human mast cell histamine release by β-adrenergic receptor agonists
β-adrenergic receptor agonist histamine release human cultured mast cells protein kinase A protein kinase C
2010/11/24
Stimulation of mast cells induced the elevation of intracellular cytosolic free Ca2+ concentrations ([Ca2+]i) and the translocation of protein kinase C (PKC) from the cytosol to the cell membrane, fol...
Dose-response relationship for inhaled corticosteroids and the add-on effect of long-acting β2-adrenergic receptor agonists in adult chronic asthmatics
add-on effect bronchial asthma dose-response relationship inhaled corticosteroids long-acting β2adrenergic receptor agonist
2010/11/22
Therapy with inhaled corticosteroids (ICS) has been regarded as first-line treatment for persistent asthma because of its highly potent anti-inflammatory effects. However, the limitations of such ther...
IL-13/IL-13 Receptor Interaction, an Emerging Therapeutic Target in Allergic Disease
allergy antagonist asthma drug design interleukin-13 receptor
2010/11/19
Interleukin (IL)-13 is a Th-2 cytokine, known to be involved in allergic diseases. Although IL-13 and another Th-2 cytokine, IL-4, share receptors and signal pathways, having similar biological proper...
The High Affinity IgE Receptor (FcεRI) as a Target for Anti-allergic Agents
FcεRI gene expression humanized anti-FcεRI α chain antibody IgE soluble α
2010/11/19
Prevention of the effector cell activation via high affinity IgE receptor (FcεRI) is thought to be a straightforward strategy for suppressing the allergic reaction. Among the numerous methods to preve...