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N-methylpurine DNA glycosylase overexpression increases alkylation sensitivity by rapidly removing non-toxic 7-methylguanine adducts
N-methylpurine DNA glycosylase alkylating agents cancer therapeutics
2014/12/12
Previous studies indicate that overexpression of N-methylpurine DNA glycosylase (MPG) dramatically sensitizes cells to alkylating agent-induced cytotoxicity. We recently demonstrated that this sensiti...
Research discovers non-toxic cancer treatment（图）
cancer treatment The interferon alpha protein
2014/7/9
A University of Queensland researcher is developing a “Trojan horse” non-toxic treatment for human breast cancer.
Toxic Methemoglobinemia Treated with Ascorbic Acid: Case report
Methemoglobinemia Prilocaine Ascorbic Acid
2015/10/9
Methemoglobinemia is a disorder characterized by the presence of a higher than normal level of methemoglobin. Prilocaine which is one of the oxidizing local anaesthetics is widely used in many local p...
THE IMPACT OF TOXIC HEAVY METALS ON THE HEMATOLOGICAL PARAMETERS IN COMMON CARP (CYPRINUS CARPIO L.)
Heavy metals hematology blood glucose common carp Cyprinus carpio L.
2009/12/14
The aim of the present investigation was to determine the effect of heavy metal pollutants such as cadmium, chromium, nickel and lead in aquatic system on common carp (Cyprinus carpio L.) by using a s...
The Status of Trace and Toxic Elements in Biological Samples (Scalp Hair) of Skin-Disease Patients and Normal Subjects
Trace elements toxic elements skin disease scalp hair atomic absorption spectrophotometer
2009/6/19
Background: Direct association of trace and macro-elements in relation to human disease has been observed in many research studies. In many cases, an alteration in the metabolism of these minerals has...
Analysis of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in Japan from 2000 to 2006
cause mortality Stevens-Johnson syndrome toxic epidermal necrolysis treatment
2010/11/18
Background: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe adverse drug reactions with high mortality.
Methods: To present the current clinical characteristics and tre...
Fetal Exposures to Toxic Releases and Infant Health
Fetal Exposures Toxic Releases Infant Health
2014/3/18
Every year, millions of pounds of toxic chemicals thought to be linked to developmental problems in fetuses are released into the air. Yet, wehave only limited information about the health effects of ...
Toxic Epidermal Necrolysis and Stevens Johnson Syndrome: Our Current Understanding
apoptosis Fas intravenous immunoglobulin Lyell's syndrome Severe adverse drug reaction
2010/11/18
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN, Lyell's syndrome) are now considered to be distinct clinical entities within a spectrum of adverse cutaneous drug reactions of incre...