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探索非特异性肝脏炎症诱导BALB/c小鼠产生自身免疫性肝炎(AIH)的原因。方法:尾静脉注射质粒pCYP2D6、pcDNA3.1和psTLR2/4,腹腔重复注射四氯化碳(CCl4)。ELISA检测抗CYP2D6抗体和自身抗体水平;HE染色检测肝脏炎症情况;天狼星红染色检测肝脏纤维化情况。
The Role of Overproduction of Nitric Oxide in Apoptosis of BALB/C Mice Macrophages Infected with LeishmaniaMajor in Vitro
Nitric Oxide Apoptosis BALB/C Mice Macrophages LeishmaniaMajor
2010/4/26
Nitric oxide (NO) derived from activated macrophages has been shown to be crucial for the host's leishmanicidal activities. Excess NO, however, can in¬duce apoptosis in some cell types, including ...