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Mandible matrix necrosis in beagle dogs After 3-years of daily oral bisphosphonate treatment
osteonecrosis of the jaw remodeling suppression
2014/12/4
Purpose An increasing number of reports have implicated bisphosphonates as contributing to osteonecrosis of the jaw. The goal of this study was to evaluate mandible necrosis in beagle dogs treated for...
Ovariectomy Stimulates and Bisphosphonates Inhibit Intracortical Remodeling in the Mouse Mandible
BRONJ jaw necrosis osteonecrosis
2014/12/4
Objective – The pathophysiology of osteonecrosis of the jaw (ONJ) is thought to be linked to suppression of intracortical remodeling. The aim of this study was to determine whether mice, ...
Implantation of Octacalcium Phosphate Stimulates both Chondrogenesis and Osteogenesis in the Tibia,but Only Osteogenesis in the Rat Mandible
Endochondral bone Intramembranous bone Chondrogenesis
2010/4/7
Statement of problem: It is not known whether endochondral and intramembranous bones have distinct biological characteristics. Octacalcium Phosphate (OCP), a hydroxyapatite precursor, has been reporte...