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Genomic studies of cancer patients have revealed thousands of mutations linked to tumor development. However, for the vast majority of those mutations, researchers are unsure of how they contribute to...
北京市神经外科研究所江涛教授团队联合中国医科大学第一附属医院吴安华教授团队于2017年10月在Clinical Cancer Research(IF:9.619)上发表论文,题目为“Tumor Purity as an Underlying Key Factor in Glioma”。该研究通过整合5个数据库、2249例脑胶质瘤组织样本的基因表达谱数据及对应的临床、基因拷贝数、基因突变等多维组学数...
Paralemmin Splice Variants and mRNA and Protein Expression in Breast Cancer.
Oncology researchers studying gene mutations in the childhood cancer neuroblastoma are refining their diagnostic tools to predict which patients are more likely to respond to drugs called ALK inhibito...
The influence of DNA cis-regulatory elements on a gene's expression has been intensively studied. However, little is known about expressions driven by trans-acting DNA hotspots. DNA hotspots harboring...
Researchers at The University of Queensland have helped identify genes that could hold the key to treating a common and deadly type of breast cancer. The discovery suggests a vaccine could be develope...
A gene-based test is now available to identify smokers and ex-smokers at greatest risk of getting lung cancer. The test is the first in the world to provide a personalised estimate of lung cancer ris...
摘要为探讨肿瘤抑制基因APC结构及表达异常与胃癌发生、发展的关系,采用ARMS PCR检测胃癌中APC基因I1307K突变存在与否,免疫组织化学方法分析胃癌中APC蛋白表达水平。结果表明,在 62例胃癌高发区易感人群血液标本及45例胃癌中未检测到I1307K突变;胃癌(早期、进展期)中APC蛋白表达阳性率显著低于正常黏膜,进展期胃癌中APC蛋白表达阳性率显著低于早期胃癌,淋巴结转移阳性的胃癌中AP...
专著信息 书名 Improved efficacy of DNA vaccination against breast cancer by boosting with the repeat beta-hCG C-terminal peptide carried by mycobacterial heat-shock protein HSP65. 语种 英文 撰写或编译 作者 Yi H,Rong Y...
期刊信息 篇名 Exon 3 polymorphisms and haplotypes of O(6)-methylguanine-DNA methyltransferase and risk of bladder cancer in southern China: A case-control analysis 语种 英文 撰写或编译 撰写 作者 Li C,Liu J,Li A,Qian L,W...

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