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清华大学医学院曾文文课题组发表题为“Neuroimmune regulation of white adipose tissues"长文综述（图）
脂肪组织 清华大学医学院 树突状细胞
2023/6/16
2021年9月26日，清华大学医学院、清华大学免疫学研究所曾文文课题组于《The FEBS Journal》在线发表题为“Neuroimmune regulation of white adipose tissues”的长文综述。综述重点介绍了白色脂肪组织中免疫细胞与支配神经的研究进展，概述了白色脂肪组织的神经免疫调节作用。
The regulation of allergic airway disease by type V collagen-induced tolerance
IL-17 Type V Collagen
2015/5/21
Tissue remodeling and complement activation are asthma hallmarks. Type V collagen [col(V)], a cryptic antigen, becomes exposed during lung remodeling. IL-17 is key to anti-col(V) immunity, and regulat...
Characterization of arachidonic acid -mediated signal transduction in regulation of NIH -3T3 cell adhesion to extracellular matrix
Matrix the discrete form cells cell proliferation lipid protein cell fibronectin
2014/12/11
Cell-extracellular matrix (ECM) adhesion is characterized by discrete morphological and functional stages beginning with cell-substrate attachment, followed by cell spreading and then migration. These...
EGFR expression and activation in bovine cumulus cells and EGFR intramolecular regulation through interactions between tyrosines
Epidermal growth factor receptor the process of cell the cell cycle cell migration cell metabolism cell proliferation oocytes and embryo development activation of cumulus cells
2014/12/11
The epidermal growth factor receptor (EGFR) plays important roles in the control of many fundamental cellular processes including cell cycle, cell migration, cell metabolism and survival, cell prolife...
Regulation of p53 by Mdm4 and ovarian hormones in mouse mammary glands
P53 protein genome cell cycle DNA cell apoptosis cell growth breast cancer
2014/12/11
p53 protein is considered a major player in maintaining the genomic integrity. It regulates cell cycle, recognizes damaged DNA, and promotes apoptosis of cells that are defective or developmentally pr...
Modulation of Nhlh2 expression by energy availability leads to downstream effects on body weight regulation
The hypothalamus transcription factors nerve energy hormone neurons arcuate nucleus neurons
2014/12/11
Mice with a deletion of the hypothalamic basic helix-loop-helix transcription factor Nhlh2 (N2KO) display adult onset obesity, implicating Nhlh2 in the neuronal circuits regulating energy availability...
The role of inositol 1,4,5 -trisphosphate receptor type-1 in regulation of intracellular calcium oscillations in mouse eggs
Calcium mammals fertilization eggs activation embryonic development cell cycle inositol receptor
2014/12/11
Calcium ([Ca2+]i) oscillations, a hallmark of mammalian fertilization, are essential to induce egg activation and embryonic development. As the zygotes transition through the cell cycle, these [Ca 2+]...
The role of GTP regulation in chloroplast import
Chloroplasts organelles plant cells photosynthesis amino acids lipid synthesis cell signal
2014/12/11
Plastids (e.g. chloroplasts) are a diverse group of interrelated organelles that have evolved to perform numerous and diverse metabolic processes within all plant cells, including essential roles in p...
Genetic studies of the regulation of RecA activity in Escherichia coli: A two filament model
E. coli protein compound enzyme DNA repair bacteria
2014/12/11
The RecA protein of Escherichia coli is a central enzyme in recombination and SOS induction, both crucial DNA repair pathways. Furthermore, RecA and its homologues are found in all domains of life, fr...
Hormones, growth factors, and the regulation of tumor suppressor pathways involved in parity -induced protection of breast cancer
Women with breast cancer cases diagnosis and reproduction exogenous hormones ionizing radiation genetic factors
2014/12/11
Despite current advances in understanding breast cancer, in 2007 an estimated 178,480 new cases were diagnosed in female patients in the United States, and an estimated 40,640 deaths will occur due to...
Regulation of Notch signaling by the E3 ubiquitin ligase Cbl-b and its role in CD4+ T cell anergy
Cell life cycle T cell signal T cell activation and E3 ubiquitin ligase
2014/12/11
Notch signaling is an evolutionarily conserved pathway that mediates a variety of cell fate decisions. In the immune system, the Notch pathway plays an important role throughout the life of T cells. C...
Regulation of RecA-dependent homologous recombination by 3'-5' exonucleases and the UvrD helicase in Escherichia coli K-12
Cell repair DNA damage cell genetic cellular regulation molecular mechanisms
2014/12/11
Homologous recombination is generally considered a major mechanism by which cells repair many types of DNA lesions and damaged replication forks. However, if this process is left unchecked, cells ofte...
Probing The Regulation Of Vasculogenic Mimicry In Glioblastoma: Implications For Treatment In Patients
Health and environmental sciences Biological sciences Angiogenesis Anti-angiogenic treatment resistance Cancer Cancer stem cells Glioblastoma Vasculogenic mimicry
2014/12/10
Glioblastoma, previously known as Glioblastoma Multiforme (GBM), is a highly angiogenic tumor and is defined pathologically by its ability to create microvascular proliferations. Patients with gliobla...
Regulation of the Hypothalamic Precursor Cells by HH/GLI Signaling in Post-Embryonic Zebrafish
Biological sciences Health and environmental sciences Heat-shock Hedgehog signaling Hypothalamus Neurogenesis Transgenic
2014/12/10
The major goals of my research were to characterize the hypothalamic neural progenitors and to understand how Hh/Gli signaling plays a role in regulating cell proliferation in the hypothalamic neuroge...
Regulation of Eg5 and TPX2 During Mammalian Mitosis
Biological sciences Eg5 Kinesin-5 Microtubule Mitosis Spindle Tpx2
2014/12/10
During mitosis, the microtubule cytoskeleton is completely rearranged to form a bipolar spindle that functions to congress and segregate a complete set of genetic material into two nascent daughter ce...