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Reproductive aging in the male Brown Norway (BN) rat is characterized by decreased Leydig cell steroidogenesis associated with seminiferous tubule dysfunction. This could be a result of a combination ...
An investigation was undertaken to determine whether the germ-cell loss associated with exposure of the testis to abdominal temperature occurs by apoptosis. Using an adult-mouse model of experimenta...
Leptin-deficient (ob/ob) male mice are morbidly obese and exhibit impaired reproductive function. The objective of this study was to assess the effect of a leptin deficiency on testicular morphology...
Surgical induction of cryptorchidism in experimental animals causes testicular germ cell apoptosis and infertility. The mechanisms of germ cell apoptosis have been associated with oxidative stress o...
We have previously demonstrated that mild testicular hyperthermia induces stage-specific and germ cell—specific apoptosis in rat and mouse testes. The objectives of this pilot study were to examine wh...
Stages at which DNA synthesis and germ cell death take place have recently been found to be equivalent in rabbits and rats. Preservation of the timing of these processes in different orders of mamma...
A deeper understanding of the occurrence of some events, such as DNA replication or germ cell apoptosis during spermatogenesis, is important for improving our understanding of seminiferous epitheliu...
Testicular germ cell apoptosis in the cryptorchid testis is induced by abdominal heat stress. p53-dependent apoptosis appears responsible for the initial phase of germ cell loss in experimental cryp...

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