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Estradiol and plasminogen activator secretion by cultured rat Sertoli cells in response to melanocyte-stimulating hormones
Estradiol and plasminogen activator secretion cultured rat Sertoli cells melanocyte-stimulating hormones
2009/2/23
Pro-opiomelanocortin-derived peptides, alpha-MSH and beta-endorphin, are synthesized and secreted by Leydig cells, and are believed to have paracrine effects on Sertoli cells in the testis. Peptid...
Endocrine parameters, hormone receptors, and functions of the testicular interstitium and seminiferous epithelium in estradiol-immunized Ile-de-France rams
gonadotropin secretion Leydig cells Sertoli cells FSH receptors androgen receptors
2009/2/23
The testicular response of Ile-de-France rams actively immunized against estradiol (E2) was evaluated during both the ovine nonbreeding season (spring) and breeding season (autumn). Plasma concentrati...
Follicle stimulating hormone, luteinizing hormone and testicular Leydig cell responses to estradiol immunization in Ile-de-France rams
Follicle stimulating hormone luteinizing hormone testicular Leydig cell estradiol immunization Ile-de-France rams
2009/2/23
Active immunization of Ile-de-France rams against estradiol (E2) resulted in the production of E2-neutralizing antibodies and an elevation in the plasma concentrations of FSH, LH, and testosterone...
Regulation of gonadotropin secretion in the male: effect of an aromatization inhibitor in estradiol-implanted, orchidectomized dogs
gonadotropins testosterone estradiol aromatase aminoglutethim
2009/2/23
Testosterone is aromatized to estradiol in both peripheral tissues and the central nervous system. Various authors have suggested that this conversion in the male may be prerequisite for the regulat...
Increased plasma and pituitary prolactin concentrations in adult male rats with selective elevation of FSH levels may be explained by reduced testosterone and increased estradiol production
Increased plasma pituitary prolactin concentrations adult male rats
2009/2/23
The roles of testosterone and estradiol in regulating prolactin concentrations were studied in acutely castrated adult male rats receiving subcutaneous Silastic implants of the sex steroids. Testost...
Cytoplasmic estradiol binding sites in testis of fertile and infertile men
estradiol receptors human testis receptor ontogenesis Leydig cell function human testicular disorders testicular cytosolic receptors
2009/2/20
Free cytoplasmic estradiol receptor was determined in testicular biopsies from six adults showing various primary testicular disorders, and in testicular tissue obtained at autopsy from 18 males of ...
Regulation of gonadotropin secretion in the male dog. Role of estradiol
gonadotropin secretion male dog
2009/2/19
Steroid regulation of pituitary LH and FSH secretion in the male may be mediated via the direct action of testosterone, or via the conversion of testosterone to either dihydrotestosterone (DHT) or e...
Influence of estradiol on accessory reproductive organs in the castrated male rat. Effects of bromocriptine and flutamide
estradiol accessory reproductive organs castrated male rat
2009/2/19
Estradiol partially maintained the weights of the dorsolateral prostate and seminal vesicles in castrated adult male rats. One group of animals received subcutaneous injections of estradiol (0.01 ...
Temporal Dissociation of Feedback and Direct Testicular Effects of Estradiol Benzoate in Male Rats
estradiol negative feedback direct testicular effects testicular incubations
2009/2/19
Studies were conducted to characterize the responses of the hypothalamic-pituitary-testicular axis to systemic injection of estradiol benzoate (EB) in the rat. Feedback effects of estrogens on the...
Effect of Estradiol on the Rat Prostate in the Presence and Absence of Testosterone and Pituitary
prostate rat estradiol testosterone pituitary prolactin
2009/2/19
In an attempt to elucidate the effect of estradiol on the rat prostate, four experiments were conducted. In experiment 1, rats were orchiectomized and were given subcutaneous implants of silastic ...
Estradiol-induced Inhibition of Testosterone Production by Testicular Interstitial Cells Incubated In Vitro
testosterone interstitial cells estradiol testis steroidogenesis
2009/2/18
Testosterone production by testicular interstitial cells incubated in vitro in the presence of 10-8 to 10-6 M 17-estradiol (E2), 17 -estradiol-3-benzoate (E2B), or benzoic acid (B) was examined. Hig...
Estradiol and high-dose dihydrotestosterone treatment causes changes in cynomolgus monkey prostate volume and histology identical to those caused by testosterone alone
Male transrectal ultrasonography androgens estrogens
2009/2/18
To evaluate the effects of testosterone (T), dihydrotestosterone (DHT), and estradiol (E2) on the regulation of prostate growth and tissue composition, the following study was conducted in a nonhuma...
Sodium chlorate induces undersulfation of cellular proteoglycans and increases in FSH-stimulated estradiol production in immature rat Sertoli cells
Sodium chlorate cellular proteoglycans FSH-stimulated estradiol production immature rat Sertoli cells
2009/2/18
The functional influence of cell proteoglycan (PG) undersulfation on estradiol synthesis by immature rat Sertoli cell cultures was investigated by using sodium chlorate, an inhibitor of the active s...
Effect of chorionic gonadotropin and flutamide on Leydig cell and macrophage populations in the testosterone-estradiol-implanted adult rat
chorionic gonadotropin Leydig cell macrophage populations testosterone-estradiol-implanted adult rat
2009/2/17
The objective of this study was to investigate the role of androgens and nonandrogenic Leydig cell products in maintaining Leydig cell and macrophage numbers in the testis of the adult rat. Adult ...
Changes in the endocrinological milieu after clomiphene citrate treatment for oligozoospermia：the clinical significance of the estradiol/testosterone ratio as a prognostic value
E5/T ratio clomiphene citrate male infertility
2009/2/12
We have already reported that the rate of increase in the estradiol/testosterone ratio (E2/T ratio) following human chorionic gonadotropin (hCG) injection has prognostic value in the treatment of olig...