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Evidence for a role of cyclooxygenase（prostaglandin synthetase）and prostaglandins in the sperm acrosome reaction and fertilization
spermatozoa fertilization acrosome reaction cyclooxygenase prostaglandin inhibitor
2009/2/23
Three cyclooxygenase (prostaglandin synthetase) inhibitors, indomethacin, phenylbutazone, and oxyphenbutazone, decreased fertilization in vitro when mixed with capacitated mouse spermatozoa before a...
The human sperm acrosome reaction does not depend on arachidonic acid metabolism via the cyclooxygenase and lipoxygenase pathways
human spermatozoa acrosome reaction arachidonic acid eicosanoids cyclooxygenase lipoxygenase
2009/2/11
The objective of this study was to determine whether the metabolism of arachidonic acid via the cyclooxygenase pathway, the lipoxygenase pathway, or both has a pivotal role in the human sperm acro...