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Screening for Genotoxicity and Oestrogenicity of Endocrine Disrupting Chemicals in Vitro
Four Endocrine Disrupting Chemicals (EDCs) Proliferation Mutagenicity DNA Strand Breakage Comet Assay DNA Repair Unscheduled DNA Synthesis Assay (UDS) E-SCREEN Assay YES Assay MVLN Assay
2013/3/11
A diverse range of endocrine disrupting chemicals (EDCs) was examined, using an in vitro test system, for critical events required for the onset of carcinogenesis in vivo. The initiation stage of carc...
Monitoring of Genotoxicity in Drinking Water Using in vitro Comet Assay and Ames Test
genotoxicity drinking water in vitro comet assay
2009/3/16
A screening strategy for evaluation of genotoxic potential of drinking water has been proposed in the present work. Genotoxicity assays with tap water collected at three different sampling points in L...
转基因植物检测体系在环境污染物突变性评价中的应用The Application of Transgenic Plant in Evaluating the Genotoxicity of Environmental Contaminants
环境检测 转基因工程 GUS基因 基因毒性
2008/1/8
摘要
很多环境污染物都能对生物体产生诱变性，可利用多种测试材料与方法对其基因毒性进行检测。转基因植物检测体系不仅能对环境污染的诱变性大小进行评价，而且还可以进一步分析其突变的分子机理。本文介绍了转基因植株检测体系的应用前景。
Abstract: Environmental contaminants are powerful mutagenic factors for organisms. Se...