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Cellular strategies of protein quality control
Cellular strategies protein quality control
2015/12/11
Eukaryotic cells must contend with a continuous stream of misfolded proteins that compromise the cellular protein homeostasis balance and jeopardize cell viability. An elaborate network of molecular c...
The role of N -linked glycans in protein quality control in the early secretory pathway
ER quality protein abnormal protein protein degradation the cavity cytosol proteasome chitosan tyrosine
2014/12/11
The ER quality control machinery maintains the fidelity of the protein maturation process by sorting aberrant proteins for ER-associated protein degradation (ERAD), a process requiring retranslocation...