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Genetic influences on schizophrenia and subcortical brain volumes:large-scale proof of concept
schizophrenia subcortical brain volumes large-scale proof of concept
2016/5/3
Schizophrenia is a devastating psychiatric illness with high heritability. Brain structure and function differ, on average, between people with schizophrenia and healthy individuals. As common genetic...
Hypomethylation of the Paternally Inherited LRRTM1 Promoter Linked to Schizophrenia
epigenetics parental imprint sibling pair psychosis
2015/5/5
Epigenetic effects on psychiatric traits remain relatively understudied, and it remains unclear what the sizes of individual epigenetic effects may be, or how they vary between different clinical popu...
Population-based linkage analysis of schizophrenia and bipolar case–control cohorts identifies a potential susceptibility locus on 19q13
schizophrenia segmental sharing case–control genome scan
2015/4/8
Population-based linkage analysis is a new method for analysing genomewide single nucleotide polymorphism (SNP) genotype data in case–control samples, which does not assume a common disease, common va...
A schizophrenia-associated HLA locus affects thalamus volume and asymmetry
Psychiatry Thalamus Hippocampus
2015/12/18
Genes of the Major Histocompatibility Complex (MHC) have recently been shown to have neuronal functions in the thalamus and hippocampus. Common genetic variants in the Human Leukocyte Antigens
(HLA) ...