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A set of regulatory genes co-expressed in embryonic human brain is implicated in disrupted speech development
Genetic disorders FOXP2 language barriers genome sequencing the children's speech apraxia
2018/3/5
Genetic investigations of people with impaired development of spoken language provide windows into key aspects of human biology. Over 15 years after FOXP2 was identified, most speech and language impa...
Association analysis of dyslexia candidate genes in a Dutch longitudinal sample
SNPs dyslexia candidate genes
2017/8/25
Dyslexia is a common specific learning disability with a substantive genetic component. Several candidate genes have been proposed to be implicated in dyslexia susceptibility, such as DYX1C1, ROBO1, K...
Asymmetry within and around the human planum temporale is sexually dimorphic and influenced by genes involved in steroid hormone receptor activity
Planum temporale Asymmetry
2015/12/18
The genetic determinants of cerebral asymmetries are unknown. Sex differences in
asymmetry of the planum temporale (PT), that overlaps Wernicke's classical language area,
have been inconsistently re...
Asymmetry within and around the human planum temporale is sexually dimorphic and influenced by genes involved in steroid hormone receptor activity
Planum temporale Asymmetry Genome-wide association scan Sexual dimorphism Steroid hormones
2015/5/13
The genetic determinants of cerebral asymmetries are unknown. Sex differences in asymmetry of the planum temporale (PT), that overlaps Wernicke's classical language area, have been inconsistently repo...
Genome wide identification of Fruitless targets suggests a role in upregulating genes important for neural circuit formation
Genome wide identification upregulating genes neural circuit
2015/5/6
The fruitless gene (fru) encodes a set of transcription factors (Fru) that display sexually dimorphic gene expression in the brain of the fruit-fly; Drosophila melanogaster. Behavioural studies have d...
Association study of fibroblast growth factor genes and brain volumes in schizophrenic patients and healthy controls
fibroblast growth brain volumes schizophrenic patients healthy controls
2015/5/6
Fibroblast growth factors (FGFs) play crucial roles in brain development and neuroprotection and have been implicated in the susceptibility to schizophrenia (Terwisscha van Scheltinga et al., 2010). F...
No effect of schizophrenia risk genes MIR137, TCF4, and ZNF804A on macroscopic brain structure
miR-137 TCF4 ZNF804A Genetic neuroimaging Brain volume
2015/5/5
Single nucleotide polymorphisms (SNPs) within the MIR137, TCF4, and ZNF804A genes show genome-wide association to schizophrenia. However, the biological basis for the associations is unknown. Here, we...
Genes: Interactions with Language on Three Levels—Inter-Individual Variation, Historical Correlations and Genetic Biasing
Interactions with Language Three Levels Inter-Individual Variation Historical Correlations Genetic Biasing
2015/4/27
The complex inter-relationships between genetics and linguistics encompass all four scales highlighted by the contributions to this book and, together with cultural transmission, the genetics of langu...
Common Variants in Left/Right Asymmetry Genes and Pathways Are Associated with Relative Hand Skill
Common Variants Left/Right Asymmetry Genes Pathways Are Associated Relative Hand Skill
2015/4/24
Humans display structural and functional asymmetries in brain organization, strikingly with respect to language and handedness. The molecular basis of these asymmetries is unknown. We report a genome-...
Computational identification of new structured cis-regulatory elements in the 30-untranslated region of human protein coding genes
Computational identification cis-regulatory elements the 30-untranslated region human protein coding genes
2015/4/20
Messenger ribonucleic acids (RNAs) contain a large number of cis-regulatory RNA elements that function in many types of post-transcriptional regulation. These cis-regulatory elements are often charact...
Are Languages Really Independent from Genes? If Not, What Would a Genetic Bias Affecting Language Diversity Look Like?
Genes Languages
2015/4/10
It is generally accepted that the relationship between human genes
and language is very complex and multifaceted. This has its roots in the
“regular” complexity governing the interplay among genes a...
Leucine-Rich Repeat Genes and the Fine-Tuning of Synapses
Synapses Leucine-Rich Repeat Genes
2015/4/10
Presynaptic neurexins and postsynaptic neuroligins are celladhesion proteins that interact across the synaptic cleft and
influence synaptic function (1). These proteins have received
recent at...